| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 606807 | Journal of Colloid and Interface Science | 2015 | 7 Pages |
•Gold micro and nano structures implemented on a silica substrate were selectively functionalized.•Large sets of individual nanoparticles were specifically trapped onto wide arrays of gold nanostructures.•68.8% of gold nanotructures had captured at least one nanoparticle.
Latex nanoparticles (100 nm and 200 nm diameter) were precisely located onto the gold regions of micro and nanopatterned gold/silica substrates through surface chemical functionalizations. The gold patterns were selectively functionalized with alkylthiols bearing biotin or amine headgroups. This selective functionalization allowed the trapping of streptavidin- or carboxy-functionalized latex nanoparticles onto the gold structures with very little non-specific adsorption onto the surrounding silica. Quantitative data of nanoparticle capture on gold and silica, obtained through SEM image analysis, showed a one to two order of magnitude increase on gold with a similar low coverage on silica (non-specific adsorption) thanks to chemical functionalizations. Single nanoparticles were captured at the gap of dimer gold nanostructures.
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