Synthesis of gold nanoparticles in niosomes

This work outlines a novel method for the synthesis of stable gold nanoparticles within the spatially confined region of vesicles. For the first time, Span/cholesterol based niosomes have been used for nanoparticle synthesis. The restricted geometry within niosomes prevents nanoparticle aggregation. The results have important implications for controlled delivery of nanoparticles for therapeutic applications.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (45 K)Download as PowerPoint slideHighlights► Gold nanoparticles were synthesized in Span-based niosomes. ► Stable, crystalline GNPs have been produced by this method. ► The niosomal cavity provides good control over nanoparticle size and shape. ► β-cyclodextrin extracts out cholesterol from the niosomal bilayer.