Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
608223 | Journal of Colloid and Interface Science | 2012 | 11 Pages |
Abstract
⺠Drug-bile salt interactions were explored by micellization and spectroscopic studies. ⺠Mixed micelles formed at lower cmc values, thus enhancing the bioavailability of drugs. ⺠Synergistic interactions have been observed for all drug-bile salt systems. ⺠Stoichiometric ratio of these complexes estimated to be 1:2 from spectroscopic studies. ⺠The binding constants for drug-bile salt complexes have been determined.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Suruchi Mahajan, Rakesh Kumar Mahajan,