Article ID Journal Published Year Pages File Type
608223 Journal of Colloid and Interface Science 2012 11 Pages PDF
Abstract
► Drug-bile salt interactions were explored by micellization and spectroscopic studies. ► Mixed micelles formed at lower cmc values, thus enhancing the bioavailability of drugs. ► Synergistic interactions have been observed for all drug-bile salt systems. ► Stoichiometric ratio of these complexes estimated to be 1:2 from spectroscopic studies. ► The binding constants for drug-bile salt complexes have been determined.
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
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