Article ID Journal Published Year Pages File Type
608766 Journal of Colloid and Interface Science 2011 10 Pages PDF
Abstract

The interaction of the antioxidant Rutin with the radical DPPH (2,2-diphenyl-1-picrylhydrazyl) in presence of cationic (CTAB, TTAB, DTAB), non-ionic (Brij78, Brij58, Brij35), anionic (SDS) and mixed surfactant systems (CTAB-Brij58, DTAB-Brij35, SDS-Brij35) has been followed by spectrophotometric and tensiometric methods to evaluate the DPPH radical scavenging activity (RSA) of Rutin in these model self-assembled structures. The results show that the solubilization capacity of various single surfactant systems for both DPPH as well as Rutin followed the order cationics > non-ionics > anionic. The radical scavenging activity of Rutin in the solubilized form was higher within ionic micelles than in non-ionic micelles. However, the antioxidant exhibited enhanced activity for the radical in mixed cationic–non-ionic micelles compared with any of the single component micelles. In contrast, anionic–non-ionic mixed micelles modulated the activity of Rutin in-between that seen for pure anionic and non-ionic micelles only.

Graphical abstractWe report herein the correlation between the interaction of Rutin with different surfactant systems and its antioxidant activity against DPPH.Figure optionsDownload full-size imageDownload high-quality image (113 K)Download as PowerPoint slideHighlights► Evaluation of solubilization characteristics of Rutin and DPPH in micellar media. ► Evaluation of antioxidant activity of Rutin against DPPH in the micellar media. ► Correlation between the solubilization and antioxidant activity results. ► Cationic surfactants were efficient solubilizers for both Rutin and DPPH. ► Cationic- nonionic systems enhanced the activity over their single counterparts.

Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
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