Article ID | Journal | Published Year | Pages | File Type |
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608805 | Journal of Colloid and Interface Science | 2011 | 7 Pages |
In this work, a novel and facile method for covalent attachment of biomaterials to graphene oxide sheets (GOS) was developed. Four conjugates were obtained via the diimide-activated amidation reaction under ambient conditions. Final products were characterized by FT-IR spectroscopy, atomic force microscopy and transmission electron microscopy. Electrochemical characterization of the composite showed that the covalently bonded biomaterial retained its bioactivity. This method may provide a way for further preparation of graphene-based biodevices.
Graphical abstractA novel and facile method for attachment of biomaterials to graphene oxide sheets was developed. The covalently bonded biomaterial retained its bioactivity.Figure optionsDownload full-size imageDownload high-quality image (110 K)Download as PowerPoint slideResearch highlights► Diimide-activated amidation was used to attach biomaterials to graphene oxide sheets. ► It causes no denaturing of the biomaterials and guaranties the uniform attachment. ► The same method can be used to introduce GOS into other biosystems.