| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 609503 | Journal of Colloid and Interface Science | 2010 | 6 Pages |
Adsorption and electrochemical reduction of pyrantel pamoate are studied in Britton Robinson buffer medium at hanging mercury drop electrode (HMDE) by Adsorptive Stripping Voltammetric technique. The peak current shows a linear dependence with the drug concentration over the range 250 ng mL−1 to 64 μg mL−1. Applicability to assay the drug in urine samples is illustrated in the concentration range 5–20 μg mL−1.
Graphical abstractCyclic voltammetry of pyrantel pamoate after pre-concentration.Figure optionsDownload full-size imageDownload high-quality image (33 K)Download as PowerPoint slideResearch highlights► The method has distinct advantages over other existing methods in terms of sensitivity, time saving and delectability. ► Can be applied to the detection of pyrantel in different pharmaceutical dosage forms. ► No sophisticated instrumentation is required. ► Good analytical alternative in comparison to spectrophotometric and chromatographic methods for determining pyrantel pamoate. ► Can be adopted for pharmacokinetic studies as well as for quality control in pharmaceutical laboratories.
