| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6099345 | Journal of Crohn's and Colitis | 2014 | 9 Pages |
Abstract
In this study in Crohn's disease patients no pharmacokinetic interaction was shown between adalimumab and the conventional thiopurines, azathioprine and mercaptopurine.
Keywords
6-MMPR6-TGNITPaseTPMTAZACDAIMCVAdalimumabTDMIMPRBCIBDHGPRTMercaptopurine6-thioguanine nucleotidesRed blood cells6-MP95% CIazathioprineinosine triphosphate pyrophosphataseCrohn's diseaseInflammatory bowel diseaseDrug interactionThiopurine S-methyltransferaseMean corpuscular volumeCrohn's Disease Activity Index95% confidence intervalInosine monophosphatetherapeutic drug monitoringhypoxanthine-guanine phosphoribosyl transferaseC-reactive proteinCRPhigh performance liquid chromatographyHPLCUlcerative colitis
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Authors
D.R. Wong, M. Pierik, M.L. Seinen, A.A. van Bodegraven, L.P.L. Gilissen, P. Bus, J.A. Bakker, A.A.M. Masclee, C. Neef, L.G.J.B. Engels, P.M. Hooymans,