| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6100172 | Journal of Crohn's and Colitis | 2012 | 10 Pages |
Abstract
OLFM4 is overexpressed in active IBD and secreted into mucus. The induction is triggered by bacteria through the Notch pathway and also by the cytokine IL-22. OLFM4 seems to be of functional relevance in IBD as a mucus component, possibly by binding defensins.
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Authors
Michael Gersemann, Svetlana Becker, Sabine Nuding, Lena Antoni, German Ott, Peter Fritz, Naohide Oue, Wataru Yasui, Jan Wehkamp, Eduard F. Stange,