Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6100212 | Journal of Crohn's and Colitis | 2013 | 4 Pages |
Abstract
We report a case of Epstein-Barr virus infection with the subsequent development of haemophagocytic lymphohistiocytosis in a teenage Crohn's disease patient treated with azathioprine. We found that the early introduction of the anti-B cell monoclonal antibody rituximab precipitated a rapid fall in circulating B-cells and EBV viral load, resulting in a prompt and sustained recovery from what is a potentially fatal complication of azathioprine therapy in Crohn's disease patients.
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Authors
Michael P. Fitzgerald, Lawrence Armstrong, Rosie Hague, Richard K. Russell,