Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6100351 | Journal of Crohn's and Colitis | 2011 | 5 Pages |
Abstract
Cyclophosphamide therapy was highly effective in steroid-refractory Crohn's colitis accompanied by Sweet's syndrome for induction of remission. Furthermore, apoptosis of mononuclear cells in the colon mucosa, including CD68+ macrophages as well as CD4+ and CD8+ cells, appears to be a component of the anti-inflammatory effect of cyclophosphamide in Crohn's disease.
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Authors
Christian Meinhardt, Jürgen Büning, Klaus Fellermann, Hendrik Lehnert, Klaus J. Schmidt,