Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6100951 | Journal of Crohn's and Colitis | 2007 | 6 Pages |
Abstract
Our study demonstrates the aberrant expression of gastric apomucins in UC and suggests that MUC5AC is associated with inflammation while MUC6 is related to the presence of neoplasia. The demonstration of metaplastic cell lineages preceding dysplasia supports the biological link between inflammation and neoplasia, MUC6 emerging as a putative biomarker of dysplasia in ulcerative colitis patients.
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Authors
Paula Borralho, Ana Vieira, João Freitas, Paula Chaves, Jorge Soares,