Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6100952 | Journal of Crohn's and Colitis | 2007 | 6 Pages |
Abstract
In patients with inflammatory bowel disease herpes simplex virus infection has been described as a major cause of morbidity and mortality, especially in immunocompromised individuals. Here we present the case of a 35-year old woman with an exacerbation of ulcerative colitis caused by herlpes simplex virus infection (HSV-2). The diagnosis was confirmed histologically following subtotal colectomy. After intravenous treatment with aciclovir for 2Â weeks postoperative hematochezia stopped. Herpes simplex virus colitis is a rare but potentially fatal complication of immunosuppressive treatment in patients with inflammatory bowel disease. Prompt diagnosis and efficient antiviral therapy are mandatory to improve prognosis.
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Authors
Marco Oliver Schunter, Thorsten Walles, Peter Fritz, Uta Meyding-Lamadé, Klaus-Peter Thon, Klaus Fellermann, Eduard Friedrich Stange, Wolfram Lamadé,