Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6120517 | Journal of Clinical Virology | 2014 | 7 Pages |
Abstract
Core-protein-specific T cell response plays an important role in chronic HBV infection. Inactive HBsAg carriers showed a much stronger core-protein-specific cytotoxic T cell response than other types of chronically infected patients. CD8+ CCR7-CD27+ T memory lymphocytes may be crucial in the immune pathogenesis of chronic HBV infection.
Keywords
PBMCHBV core proteinantibodies to hepatitis B surface antigenCHBHBsAgIL-2IFN-γIQRALTCTLASTAlanine aminotransferaseHepatitis B surface antigenhuman leucocyte antigenHLAGamma interferonInterleukin-2aspartate transaminasePeripheral blood mononuclear cellCMVcytomegalovirusAnti-HBsCytotoxic T lymphocytesinterquartile rangeHIV-1Human immunodeficiency virus type 1
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Authors
Wei Cao, Zhifeng Qiu, Ting Zhu, Yanling Li, Yang Han, Taisheng Li,