Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6121066 | Journal of Clinical Virology | 2011 | 7 Pages |
Abstract
In the majority of patients after short-term treatment with telaprevir or boceprevir wild-type NS3-protease isolates are detectable by clonal sequencing at long-term follow-up. Detectable resistance mutations in single patients are not predictable by initial frequencies of variants.
Keywords
pegylated interferon-alphaDAAPEG-IFNαQIDSVRstandard-of-careribonucleic acidRNAinterferonbase pairsRibavirinTIDWorld Health OrganizationSOCweekHBVHepatitis C virusHCVinternational unitspolymerase chain reactionPCRhuman immunodeficiency virusHIVhepatitis B virusSustained virologic responseNon-structural proteinBIDLong-term follow-upGenotypeWHO
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Authors
Simone Susser, Johannes Vermehren, Nicole Forestier, Martin Walter Welker, Natalia Grigorian, Caterina Füller, Dany Perner, Stefan Zeuzem, Christoph Sarrazin,