Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6121132 | Journal of Clinical Virology | 2013 | 6 Pages |
Abstract
Both 4th generation immunoassays demonstrated excellent performance in sensitivity, with the reduction of the serological window period (7-11 days earlier detection than the 3rd generation HIV tests). However, GS HIV Combo Ag/Ab demonstrated improved HIV antigen analytical sensitivity and slightly better specificity when compared to ARCHITECT HIV Ag/Ab Combo assay, with higher positive predictive values (PPV) for low prevalence populations.
Keywords
AFSSAPSS/CO4th generationFDAIRBPPVAgence française de sécurité sanitaire des produits de santépositive predictive valueribonucleic acidRNAenzyme immunoassayEIAWorld Health OrganizationFood and Drug Administrationconfidence intervalFalse positivesmilliliterinstitutional review boardinternational unitpolymerase chain reactionPCRSpecificityAntibodypicogramWHOGlycoprotein
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Authors
Elizabeth O. Mitchell, Greg Stewart, Olivier Bajzik, Mathieu Ferret, Christopher Bentsen, M. Kathleen Shriver,