Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6121244 | Journal of Clinical Virology | 2013 | 6 Pages |
Abstract
The increased methylation at the CpG sites in the HPV52/58 L1 gene was correlated with the severity of cervical neoplasia, similar to HPV16/18 in previous studies. These data suggest that HPV methylation status of the L1 gene is a candidate biomarker of CIN for detecting CIN2 and CIN3.
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Authors
Isao Murakami, Takuma Fujii, Katsuaki Dan, Miyuki Saito, Akiko Ohno, Takashi Iwata, Daisuke Aoki,