Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6121569 | Journal of Clinical Virology | 2013 | 6 Pages |
Abstract
There are sites of preferential HPV 16 integration. The integration sites tend to be located in repetitive regions of the host genome, and some sites are found near cancer-relevant genes. In addition, the HPV 16 genome is more likely to be disrupted in the L2 gene locus.
Keywords
HSILBCCsSCCURRLTRDIPSLSILSINEIntegrationSite preferenceLINEHigh-grade squamous intraepithelial lesionsLow-grade squamous intraepithelial lesionsLong interspersed nuclear elementsShort interspersed elementsRepetitive elementupstream regulatory regionNucleotideHuman papilloma virusHPVHuman papillomavirus 16Squamous cell carcinoma
Related Topics
Life Sciences
Immunology and Microbiology
Applied Microbiology and Biotechnology
Authors
Hui Li, Yi Yang, Ruifen Zhang, Yupin Cai, Xi Yang, Zhiyun Wang, Yuan Li, Xuemei Cheng, Xin Ye, Yang Xiang, Baoli Zhu,