Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6128755 | Anaerobe | 2013 | 25 Pages |
Abstract
The sensitivities of E. coli and S. pyogenes to LL-37 were tested under anaerobic conditions and compared to those in aerobic ones. The oxygen facultative E. coli grew to a higher density under aerobic conditions and its sensitivity to LL-37 was increased under anaerobiosis. The microaerophilic pathogen S. pyogenes grew faster and to a higher density under anaerobic conditions and was much more resistant to LL-37 under oxygen deprivation. Our results suggest that resistance to antimicrobial agents of microbes infecting anaerobic-microaerophilic sites should be tested under oxygen-restricted conditions.
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Authors
Amir Eini, Asaf Sol, Shunit Coppenhagen-Glazer, Yaniv Skvirsky, Avi Zini, Gilad Bachrach,