Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6128922 | Clinical Microbiology and Infection | 2016 | 14 Pages |
Abstract
Aspergillus spp. invasive external otitis (IEO) is a rare infection. We performed a seven-year, single-centre retrospective study from 2007 to 2014 including all patients with proven Aspergillus spp. IEO. Twelve patients were identified. All patients had a poorly controlled diabetes mellitus and one underwent solid organ transplant. The most frequently isolated species was Aspergillus flavus (n = 10) and voriconazole was the first-line therapy in all cases, with a median length of treatment of 338.5 days (158-804 days). None of the patients underwent extensive surgery. The clinical outcome was excellent. However, otological sequelae were reported, including hearing impairment (n = 7) and facial palsy (n = 3).
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Authors
E. Marchionni, P. Parize, A. Lefevre, P. Vironneau, M.E. Bougnoux, S. Poiree, H. Coignard-Biehler, S.E. DeWolf, K. Amazzough, F. Barchiesi, V. Jullien, A. Alanio, D. Garcia-Hermoso, M. Wassef, R. Kania, O. Lortholary, F. Lanternier,