Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6129225 | Clinical Microbiology and Infection | 2015 | 14 Pages |
Abstract
Blood samples were collected from 101 untreated pulmonary tuberculosis (TB) patients and 101 age- and sex-matched healthy control subjects. TB patients had lower lymphocyte and a higher monocyte counts than control subjects (p <0.0001 for both). The seropositive rate of human herpesvirus (HHV) type 8 antibody was higher in patients (30/101) than in control subjects (15/101) (p = 0.01). Antibody titres in patients also exceeded those in control subjects (p 0.006). Lymphocyte and monocyte counts between seronegative and seropositive subjects were not different. Four patients were positive for HHV-8 DNA. The study revealed a significantly higher HHV-8 seroprevalence in untreated pulmonary TB patients than in general population.
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Authors
C.-C. Su, C.-L. Lai, S.-M. Tsao, M.-N. Lin, T.-C. Hsieh, J.-J. Lu, T.-Y. Chu,