Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6129338 | Clinical Microbiology and Infection | 2015 | 4 Pages |
Abstract
To assess the distribution of phylogroups and O25/ST131 in the Netherlands, we performed a real-time polymerase chain reaction (PCR) on a collection of 108 wild-type Escherichia coli (WT-EC) and 134 extended-spectrum β-lactamase-producing E. coli (ESBL-EC). Phylogroup B2 was predominant, but ESBL-EC were less likely to belong to this phylogroup (48.5%) than were WT-EC (66.7%; p = 0.005). In WT-EC, phylogroups B2 and D seem to be more virulent, having a higher prevalence among midstream urine isolates and blood culture isolates, than in catheter-related urine isolates (83.3% and 87.9% vs. 61.9%; p 0.048). O25/ST131 is associated with ESBL production, being almost absent among phylogroup B2 WT-EC (61.5% vs. 5.6%; p < 0.001).
Related Topics
Life Sciences
Immunology and Microbiology
Microbiology
Authors
I.T.M.A. Overdevest, A.M.C. Bergmans, J.J. Verweij, J. Vissers, N. Bax, E. Snelders, J.A.J.W. Kluytmans,