Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6129494 | Clinical Microbiology and Infection | 2015 | 10 Pages |
Abstract
This study reports six consecutive patients who underwent heart transplantation as salvage treatment for endocarditis (Duke criteria) with extensive perivalvular lesions and end-stage heart failure. The median age was 45 years (range, 24 to 64), and the aortic valve was affected in all patients. Pathogens were Staphylococcus aureus (n = 2), Streptococcus pneumoniae (n = 2), Streptococcus agalactiae (n = 1), or not documented (n = 1). All patients survived, with no relapse, after a median follow-up of 24.5 months. The 10 patients with heart transplantation for endocarditis previously reported also survived (median follow-up, 27.5 months). Heart transplantation may be considered as salvage treatment in selected patients with intractable infective endocarditis.
Related Topics
Life Sciences
Immunology and Microbiology
Microbiology
Authors
Marie Aymami, Matthieu Revest, Caroline Piau, Céline Chabanne, François Le Gall, Bernard Lelong, Jean-Philippe Verhoye, Christian Michelet, Pierre Tattevin, Erwan Flécher,