Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6131029 | Clinical Microbiology and Infection | 2013 | 4 Pages |
Abstract
The prevalence of Escherichia coli producing extended-spectrum β-lactamases (ESBLs) markedly increased during 2004-2008 in south-western Sweden, with a greater increase in urinary isolates in hospitals (0.2-2.5%) than in the community (0.2-1.6%). ESBLs of genotype CTX-M predominated, with a significant (p <0.02) shift from the CTX-M-9 to CTX-M-1 phylogroup occurring among urinary ESBL-producing E. coli isolated early (n = 41) as compared with late (n = 221) in the study period. The increase in ESBL-producing E. coli was polyclonal, and only partly attributable to an increase (0-24%) in the number of O25b-ST131 isolates carrying CTX-M-15. The increase was prominent in men and in elderly patients, and warrants continued surveillance.
Keywords
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Authors
L. Helldal, N. Karami, K. Florén, C. Welinder-Olsson, E.R.B. Moore, C. Ã
hrén,