| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6131115 | Clinical Microbiology and Infection | 2012 | 5 Pages |
Abstract
Comparison of genome-wide, high-resolution restriction maps of Klebsiella pneumoniae clinical isolates, including an NDM-1 producer, and in silico-generated restriction maps of sequenced genomes revealed a highly heterogeneous region we designated the 'high heterogeneity zone' (HHZ). The HHZ consists of several regions, including a 'hot spot' prone to insertions and other rearrangements. The HHZ is a characteristic genomic area that can be used in the identification and tracking of outbreak-causing strains.
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Authors
M.S. Ramirez, G. Xie, S.H. Marshall, K.M. Hujer, P.S.G. Chain, R.A. Bonomo, M.E. Tolmasky,