Article ID Journal Published Year Pages File Type
6131404 Current Opinion in Microbiology 2017 8 Pages PDF
Abstract
The crosstalk between the host and its microbiome occurs in part through the secretion of metabolites, which have a profound effect on host physiology. The immune system constantly scans the intestinal microenvironment for information regarding the metabolic state of the microbiota as well as the colonization status. Recent studies have uncovered a major role for microbial metabolites in the regulation of the immune system. In this review, we summarize the central findings of how microbiota-modulated metabolites control immune development and activity.
Related Topics
Life Sciences Immunology and Microbiology Microbiology
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