Article ID Journal Published Year Pages File Type
6131918 Current Opinion in Microbiology 2014 6 Pages PDF
Abstract
Most bacterial chromosomes and plasmids are covalently closed circular molecules that are maintained in a dynamic supercoiled state. Average supercoil density differs significantly between Escherichia coli and Salmonella. Two related questions are: What protein(s) create supercoil domain boundaries in a bacterial chromosome? and How is supercoil density regulated in different bacterial species? RNA polymerase plays pivotal roles in both of these topological phenomena.
Related Topics
Life Sciences Immunology and Microbiology Microbiology
Authors
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