| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6132003 | Current Opinion in Microbiology | 2014 | 7 Pages |
Abstract
A simple epidemiological model is used as a framework to explore the potential efficacy of measures to control antibiotic resistance in community-based self-limiting human infections. The analysis of the properties of this model predict that resistance can be maintained at manageable levels if: first, the rates at which specific antibiotics are used declines with the frequency of resistance to these drugs; second, resistance rarely emerges during therapy; and third, external sources rarely contribute to the entry of resistant bacteria into the community. We discuss the feasibility and limitations of these measures to control the rates of antibiotic resistance and the potential of advances in diagnostic procedures to facilitate this endeavor.
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Authors
Bruce R Levin, Fernando Baquero, PÃ¥l J Johnsen,