Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6132056 | Current Opinion in Microbiology | 2013 | 6 Pages |
Abstract
⺠In bacteria, the rate of transcription elongation is controlled by the rate of translation. ⺠Ribosome coupling prevents RNAP backtracking. ⺠Ribosome coupling prevents DNA damage caused by codirectional collisions between backtracked RNAP and the replisome. ⺠The NusE:NusG complex links RNAP to the 30S subunit of the ribosome. ⺠RfaH adopts a NusG-like fold when it binds to RNAP and can then bind the ribosome through interactions with NusE.
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Authors
Katelyn McGary, Evgeny Nudler,