Article ID Journal Published Year Pages File Type
6132056 Current Opinion in Microbiology 2013 6 Pages PDF
Abstract
► In bacteria, the rate of transcription elongation is controlled by the rate of translation. ► Ribosome coupling prevents RNAP backtracking. ► Ribosome coupling prevents DNA damage caused by codirectional collisions between backtracked RNAP and the replisome. ► The NusE:NusG complex links RNAP to the 30S subunit of the ribosome. ► RfaH adopts a NusG-like fold when it binds to RNAP and can then bind the ribosome through interactions with NusE.
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