Article ID Journal Published Year Pages File Type
6132070 Current Opinion in Microbiology 2013 7 Pages PDF
Abstract
► SMRT DNA sequencing allows high-resolution detection of modified nucleotides. ► Methylated loci in bacterial genomes can be comprehensively and quantitatively mapped. ► SMRT DNA analyses reveal specific sequences targeted by methyltransferases. ► Methylation status can be correlated with numerous biological processes. ► Roles for DNA methylation and methyltransferases are uncharacterized in most bacteria.
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