Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6132070 | Current Opinion in Microbiology | 2013 | 7 Pages |
Abstract
⺠SMRT DNA sequencing allows high-resolution detection of modified nucleotides. ⺠Methylated loci in bacterial genomes can be comprehensively and quantitatively mapped. ⺠SMRT DNA analyses reveal specific sequences targeted by methyltransferases. ⺠Methylation status can be correlated with numerous biological processes. ⺠Roles for DNA methylation and methyltransferases are uncharacterized in most bacteria.
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Authors
Brigid M Davis, Michael C Chao, Matthew K Waldor,