| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6132198 | Current Opinion in Microbiology | 2014 | 9 Pages |
Abstract
CRISPR-Cas systems protect prokaryotes from viruses and plasmids and function primarily as an adaptive immune system in these organisms. Recent discoveries, however, revealed unexpected roles for CRISPR loci as barriers to horizontal gene transfer and as modulators of gene expression. We review how both of these functions of CRISPR-Cas systems can affect the emergence and virulence of human bacterial pathogens.
Related Topics
Life Sciences
Immunology and Microbiology
Microbiology
Authors
Asma Hatoum-Aslan, Luciano A Marraffini,