Article ID Journal Published Year Pages File Type
6132226 Current Opinion in Microbiology 2012 7 Pages PDF
Abstract
► Replicative asymmetry of Caulobacter daughter cells is dictated by CtrA. ► Two phosphorelays drive the phosphorylation and proteolytic stabilization of CtrA. ► CckA, the kinase for CtrA, must localize to a cell pole for maximal activation. ► CckA colocalizes with the phosphatase PleC to avoid downregulation by DivK∼P. ► Localization of DivJ and PleC to opposite poles helps establish replicative asymmetry.
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