Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6132226 | Current Opinion in Microbiology | 2012 | 7 Pages |
Abstract
⺠Replicative asymmetry of Caulobacter daughter cells is dictated by CtrA. ⺠Two phosphorelays drive the phosphorylation and proteolytic stabilization of CtrA. ⺠CckA, the kinase for CtrA, must localize to a cell pole for maximal activation. ⺠CckA colocalizes with the phosphatase PleC to avoid downregulation by DivKâ¼P. ⺠Localization of DivJ and PleC to opposite poles helps establish replicative asymmetry.
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Authors
Christos G Tsokos, Michael T Laub,