| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6132242 | Current Opinion in Microbiology | 2013 | 8 Pages |
Abstract
- Apicomplexan mitochondria are greatly reduced, lacking many significant enzymes.
- The 'apicoplast' is a nonphotosynthetic secondary endosymbiotic plastid, and potentially vulnerable to therapeutic intervention.
- The 'inner membrane complex' is derived from cortical alveolae of the superphylum Alveolata, and central to these parasites' distinctive replicative mechanism.
- Microneme and rhoptry components of the apicomplexan 'apical complex' invasion machinery may be derived from secretory endosomes.
- Understanding organellar origins provides context for functional studies.
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Authors
Christen M Klinger, R Ellen Nisbet, Dinkorma T Ouologuem, David S Roos, Joel B Dacks,