Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6132243 | Current Opinion in Microbiology | 2013 | 6 Pages |
Abstract
The ability of Apicomplexan parasites to invade host cells is key to their survival and pathogenesis. Plasmodium and Toxoplasma parasites share common mechanisms for invasion of host cells. Secretion of microneme and rhoptry proteins, tight junction formation and assembly of an acto-myosin motor are key steps for successful invasion by both parasites. Here, we review our understanding of the molecular basis for these steps.
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Authors
Pushkar Sharma, Chetan E Chitnis,