Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6132384 | Current Opinion in Microbiology | 2012 | 7 Pages |
Abstract
⺠Apicomplexan parasites actively invade their host cell using actin-based motility. ⺠Host cell attachment is mediated by proteins secreted from the apical complex. ⺠Rhoptry neck (RON) proteins are inserted into the host cell membrane. ⺠The parasite cell surface protein AMA1 binds to RON2 to form a tight junction. ⺠Migration of the parasite past this 'moving junction' results in cell entry.
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Authors
Bang Shen, L David Sibley,