Article ID Journal Published Year Pages File Type
6132384 Current Opinion in Microbiology 2012 7 Pages PDF
Abstract
► Apicomplexan parasites actively invade their host cell using actin-based motility. ► Host cell attachment is mediated by proteins secreted from the apical complex. ► Rhoptry neck (RON) proteins are inserted into the host cell membrane. ► The parasite cell surface protein AMA1 binds to RON2 to form a tight junction. ► Migration of the parasite past this 'moving junction' results in cell entry.
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Life Sciences Immunology and Microbiology Microbiology
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