| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6132385 | Current Opinion in Microbiology | 2012 | 7 Pages |
Abstract
⺠Antigenic variation enables parasites to avoid the antibody response of their host. ⺠The multi-copy var gene family of P. falciparum encodes variant surface antigens. ⺠Control of var gene expression depends on modifications to chromatin structure. ⺠Recombination between var genes leads to extensive sequence diversity. ⺠Chromatin structure and DSB repair likely contribute to var gene diversification.
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Authors
Laura A Kirkman, Kirk W Deitsch,