| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6132396 | Current Opinion in Microbiology | 2012 | 6 Pages |
Abstract
⺠Numerous factors and pathways are used by the cellular RNA decay machinery to regulate transcript stability. ⺠The cellular RNA decay machinery has a significant influence on viral gene expression in infected cells. ⺠Strategies used by RNA viruses to avoid the cellular RNA decay machinery include degrading/inactivating key components, recruiting cellular stability factors and evolution of nuclease resistant RNA structures. ⺠Instead of simply avoiding it, RNA viruses may also use the cellular RNA decay machinery to increase or fine tune their gene expression.
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Authors
Stephanie L Moon, Michael D Barnhart, Jeffrey Wilusz,