Article ID Journal Published Year Pages File Type
6132428 Current Opinion in Microbiology 2011 6 Pages PDF
Abstract
► Elevated available serum iron compromises phagocyte killing of Mucorales. ► Mucorales binds to extracellular matrix proteins and invade endothelial cells. ► Iron enhances host cell invasion by increasing expression of the host receptor GRP78. ► Iron chelation therapy in animals is protective against mucormycosis.
Related Topics
Life Sciences Immunology and Microbiology Microbiology
Authors
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