Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6132440 | Current Opinion in Microbiology | 2011 | 12 Pages |
Abstract
⺠Peroxisomes catalyze diverse metabolic reactions, many of which involve lipids. ⺠Medically important viruses exploit peroxisomes in ways that are not well understood. ⺠HIV's Nef and influenza's NS1 each bind to a peroxisomal enzyme of lipid metabolism. ⺠Other viral proteins enter peroxisomes or are targeted to its surface. ⺠Peroxisomes signal the presence of intracellular virus for an innate immune response.
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Authors
Paul B Lazarow,