| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6132441 | Current Opinion in Microbiology | 2011 | 6 Pages |
Abstract
⺠A functional ubiquitin-proteasome system is required for efficient Dengue virus RNA translation and/or replication. ⺠Localization of the Dengue virus capsid protein to lipid droplets may temporally regulate virus replication and assembly. ⺠Dengue virus hijacks components of the host cell lipid metabolism and utilizes autophagy to maximize replication. ⺠The unfolded protein response is triggered and exploited by Dengue virus in a temporally regulated manner. ⺠Dengue virus evolved countermeasures to overcome the restriction imposed by the innate antiviral defense.
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Authors
Wolfgang Fischl, Ralf Bartenschlager,