| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6132489 | Current Opinion in Microbiology | 2010 | 5 Pages |
Abstract
The conserved COP9 signalosome (CSN) multiprotein complex is located at the interface between cellular signaling, protein modification, life span and the development of multicellular organisms. CSN is required for light-controlled responses in filamentous fungi. This includes the circadian rhythm of Neurospora crassa or the repression of sexual development by light in Aspergillus nidulans. In contrast to plants and animals, CSN is not essential for fungal viability. Therefore fungi are suitable models to study CSN composition, activity and cellular functions and its role in light controlled development.
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Authors
Gerhard H Braus, Stefan Irniger, Ãzgür Bayram,