Formation and electrochemical characterization of 6-thioguanosine monolayers on the mercury surface

The interfacial and electrochemical behavior of 6-thioguanosine—6-thioguanine riboside (6TGR)—on a hanging mercury drop electrode was studied with ac and cyclic voltammetry in a solution of 0.1 M Na2SO4 and 0.01 M sodium acetate buffer at pH 4.3. A self-assembled monolayer (SAM) of chemisorbed 6TGR molecules formed under determined adsorption conditions was characterized. A low-density monolayer of chemisorbed 6TGR molecules and a condensed monolayer of physisorbed ones, which are successively formed by reduction of the SAM, were also studied.

Graphical abstractA self-assembled monolayer (SAM) of chemisorbed 6-thioguanosine (6-thioguanine riboside (6TGR)) molecules, formed on hanging mercury drop electrode under determined adsorption conditions, was characterized.Figure optionsDownload full-size imageDownload as PowerPoint slide