Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6136337 | Microbial Pathogenesis | 2012 | 9 Pages |
Abstract
⺠HIV-1+ Chinese individuals, including TPs and LTNPs were included in the study. ⺠A modified co-cultures model was used to obtain more HIV-1-infected CD4+ T cells. ⺠More productive HIV-1 infection occurred in Th1 cells in HIV-1+ individuals. ⺠The excessive activation of CD4+ T cells was crucial to AIDS progression. ⺠The preferential replication of HIV-1 in Th1 cells was crucial to AIDS progression.
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Authors
Yan Li, Wenhua Ling, Huifang Xu, Ming Wang, Changyou Wu,