| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6136338 | Microbial Pathogenesis | 2012 | 9 Pages |
Abstract
⺠Constructing LcrV2345, in which five amino acid residues were replaced with glutamine. ⺠Replaing the wild-type lcrV gene on the pCD1Ap plasmid with lcrV2345 gene. ⺠Both wild-type LcrV and LcrV2345 can't elicit significant levels of IL-10 in macrophage. ⺠Immunomodulation mediated by LcrV/TLR2 interactions does not play a significant role in the pathogenicity of Y. pestis.
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Authors
Wei Sun, Roy III,