Article ID Journal Published Year Pages File Type
6136355 Microbial Pathogenesis 2012 8 Pages PDF
Abstract
► First approach towards the evaluation of Pyrazoline based transition metal complexes as anticandidal agents. ► Complex formation leads to increase in anticandidal activity. ► Drug combination with amphotericin B and fluconazole reversed the order of anticandidal activities. ► A pronounced synergism has been observed in both ligand and the complexes with the conventional antifungals. ► It is exciting to note that the fungicidal potential of normally fungistatic FLC was observed in combination therapy.
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