| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6136380 | Microbial Pathogenesis | 2012 | 11 Pages |
Abstract
⺠Innate immune response in leptospirosis in susceptible or resistant mice strains. ⺠Expression of TNF-a and CXCL2/MIP-2 occurs in early stages of Leptospira infection. ⺠The expression of the cytokines is dependent on the organ and time after infection. ⺠Control of bacterial load correlates with integrity of the innate immune system. ⺠Susceptible mice C3H/HeJ (TLR4-) present more tissue damage than parental strain.
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Authors
Josefa B. da Silva, Enéas Carvalho, Ambart E. Covarrubias, Ana Tung C. Ching, Vania G.M. Mattaraia, Delhi Paiva, Marcelo de Franco, Regiane Degan Fávaro, Martha M. Pereira, Silvio Vasconcellos, Telma T.M. Zorn, Paulo Lee Ho, Elizabeth A.L. Martins,