| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6136425 | Microbial Pathogenesis | 2011 | 6 Pages |
Abstract
⺠We demonstrate that PLA-coated leptospires interfere with complement C3b and IgG depositions on the bacterial surface. ⺠This probably occurs through the degradation of these components diminishing opsonization process. ⺠Decreasing opsonization by PLA generation might be an important aspect of the leptospiral immune escape strategy. ⺠This is the first report of proteolytic activity of plasmin associated-Leptospira related to anti-opsonic properties.
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Authors
Monica L. Vieira, Zenaide M. de Morais, Silvio A. Vasconcellos, Eliete C. Romero, Ana L.T.O. Nascimento,