Article ID Journal Published Year Pages File Type
622012 Chemical Engineering Research and Design 2011 5 Pages PDF
Abstract
▶ The aim of this study was to develop a delayed release matrix pellet containing atenolol as active pharmaceutical ingredient and to increase the bioavailability of the product. ▶ The matrix pellet additionally contained trisodium phosphate dodecahydrate as alkalizing pore-former agent to enhance the dissolution of the API at pH 6.8. ▶ The delayed release was ensured by coating with a gastroresistant polymer.
Related Topics
Physical Sciences and Engineering Chemical Engineering Filtration and Separation
Authors
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