Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6267080 | Current Opinion in Neurobiology | 2013 | 7 Pages |
Abstract
⺠CB1R plays a crucial role in drug rewarding properties and the motivation to drug-seeking behavior. ⺠CB2R modulates cocaine-rewarding properties, although the mechanism involved must be clarified. ⺠FAAH inhibitors show no abuse liability and may be potential therapeutic agents for drug addiction. ⺠A genetic tool is now available to study the role of 2-AG without changes in other endocannabinoid elements.
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Authors
Rafael Maldonado, Patricia Robledo, Fernando Berrendero,