| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6272818 | Neuroscience | 2014 | 12 Pages |
Abstract
Herein we have reviewed the available information regarding the role and function of the innate and adaptive immune responses in influencing CNS plasticity during the acute and chronic phases of after injury. We have examined how CNS damage evolves along the activation of main cellular and molecular pathways that are associated with intrinsic repair, neuronal functional plasticity and facilitation of tissue reorganization.
Keywords
NGFNVUMMPCSPGIGFNSCECMPIDBDNFMPOIFNinterleukinBBBBlood–brain barrierDendritic cellsNeural stem cellsGAPnerve growth factorInsulin-like growth factorBrain-derived neurotrophic factorExtracellular matrixMast cellsMatrix metalloproteinasesmyeloperoxidaseNeurotrophinsType 1 interferonneurovascular unitGrowth-associated proteinChondroitin sulfate proteoglycans
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Authors
L. Peruzzotti-Jametti, M. Donegá, E. Giusto, G. Mallucci, B. Marchetti, S. Pluchino,