Article ID Journal Published Year Pages File Type
6282550 Neuroscience Letters 2013 5 Pages PDF
Abstract
The human brain is a complex network that is known to be affected by normal aging. Graph-based analysis has been used to estimate functional brain network efficiency and effects of normal aging on small-worldness have been reported. This relationship is further investigated here along with network modularity, a statistic reflecting how well a network is organized into modules of densely interconnected nodes. Modularity has previously been observed to vary as a function of working memory capacity, therefore we hypothesized that both small-worldness and modularity would show age-related declines. We found that both small-worldness and modularity were negatively correlated with increasing age but that this decline was relatively slow.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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